Disclaimer:The following information is by no means to be taken as a medical advice, it is just the reporting of published data and the pros and cons.
Americans have a right to data so they can make an informed decision.
If you want to be informed on this subject, I ask you to read all articles and watch all videos represented here. If your short on time, then go to the last article as it puts everything in perspective. I give this post about a 30% chance of not being taken down.
Above is a classic picture used by psychologists and scientists to show how people when presented with the same stimuli, can come up with a completely different viewpoint.
As the saying goes “ perception is reality “
The nation’s perception of the drug hydroxychloroquine exemplifies this trial..
However, given the reporting done by the mass media, the trial would be akin,to stating before the trial.”Oh by the way, we’ve found that most people see the old lady instead of the young lady in that picture.”
This proverbial “stacking of the deck” is exactly what happened after this statement from President Trump’s address March19th, 2020.
“Right to Try has been an incredible success. But this is beyond Right to Try. If treatments known to be safe in Europe, Japan, or other nations are effective against the virus, we’ll use that information to protect the health and safety of American people. Nothing will stand in our way as we pursue any avenue to find what best works against this horrible virus.
Now, a drug called chloroquine — and some people would add to it “hydroxy-.” Hydroxychloroquine. So chloroquine or hydroxychloroquine. Now, this is a common malaria drug. It is also a drug used for strong arthritis. If somebody has pretty serious arthritis, also uses this in a somewhat different form. But it is known as a malaria drug, and it’s been around for a long time and it’s very powerful. But the nice part is, it’s been around for a long time, so we know that if it — if things don’t go as planned, it’s not going to kill anybody.
When you go with a brand-new drug, you don’t know that that’s going to happen. You have to see and you have to go — long test. But this has been used in different forms — very powerful drug — in different forms. And it’s shown very encouraging — very, very encouraging early results. And we’re going to be able to make that drug available almost immediately. And that’s where the FDA has been so great. They — they’ve gone through the approval process; it’s been approved. And they did it — they took it down from many, many months to immediate. So we’re going to be able to make that drug available by prescription or states.
There are promising therapies produced by Gilead, and that’s remdesivir. Remdesivir. And that’s a drug used for other purposes that’s been out and has had very good results for other purposes, but it seems to have a very good result, having to do with this virus. And that drug also has been approved or very close to approved, in that case, by the FDA.
Director of the National Institutes of Allergy and Infectious Diseases Dr. Anthony Fauci says, “the answer is no” when asked at a task force briefing if hydroxychloroquine is an effective coronavirus treatment, explaining signs of the drug’s promise were purely “anecdotal evidence.”
“But I’m a big fan, and we’ll see what happens,” Trump steps forward to add. “I feel good about it. That’s all it is, just a feeling, you know.”
To say that the media took this issue and went viral is an understatement to say the least.
Any study or doctor that went against the narrative, that this drug was not just ineffective but could kill you, was not just ostracized, they were censored.
Any evidence,that there could be promise was discredited.
If it didn’t meet the “Gold Standard” of a randomized double blind study, it was immaterial. If one dared to differ with the WHO(World Health Organization) you tube would take down the video.
Putting this blog together has been difficult to say the least, as I pride myself on doing the research and present the facts.
I do not have the space or time to present the “What You See vs “The Complete Story”.
There are countless articles demonizing the use hydrochloroquine,
just google it. But there are credible voices who have used this drug with good to great results. We’re going to look at those cases and let you make the call.
DR. Vladmir Zelenko
Dr. Vladimir Zelenko is probably the most public figure on the hydroxychloroquine front. One of his first interviews was with Dennis Prager on Pragers national radio show. “Doctor: Malaria Drug Has Been A “Game Changer” “shown on April 23rd, 2020. Currently Dr. Zelenko is working with 7 countries, one being Israel.
He has said he understood the need for clinical trials but added that ignoring a hopeful possibility was also risky. “I’m a strong supporter of clinical trials,” he said. “But they take time, and that’s one thing we don’t have. The virus is here, it’s World War III, and not everyone has fully comprehended that yet.”
In very simplistic terms, Dr. Zelenko’s attack on the Corovirus 19 virus is at the beginning of the attack. According to the doctor, the virus infiltrates the host and it takes 5 to 6 days to get to the point where it explodes into the system. That is his target time area. He evaluates patients and puts them into two groups. High Risk- 60 years and older or under 60 with co-morbidity and also showing symptoms Low Risk- under 60 with no health problems showing symtoms.
He states he has treated at the time of this interview 1,400 patients with Covid19, with 405 of those in the high risk group. Of the 405, he reports two deaths and the rest have recovered in various time frames, none being extensive.
He treats his high risk patients with a combination of Hydroxychloroquine, Zinc, and Erythromycin. His explanation is that this combination, when administered in the early phase, greatly inhibits the ability of the virus to duplicate in the body.
Interestingly enough, you cannot find this interview on You-Tube or Facebook as they have taken it down . See the two screen shots below. They feel that we, as citizens ,don’t have the common sense to apply the information. I mean, just because the President said it had promise, we would attempt to ingest anything with the substance in it, like fish aquarium cleaner. Remember that was done by one citizen and calls to mind the phrase “There’s no pill for Stupid”
You can view this interview by clicking on the link below or copy and paste. See if you can see why this should not be listened to.
As an example of the demonization of Dr. Zelenko, I am showing an excerpt from a blog from Billy Rubin on April 13th, 2020. Pls see Dr Zelenkos response to a video of Dr. Rubin, Which I will assume takes the same issues.
(It maybe just me, but I do seem to sense some hostility towards the president in this blog and it being somewhat judgmental) you decide.. Also one may want to check the stat Covid-19 having a 4% mortality rate, as it appears to be incorrect in today’s calculations
Billy Rubin’s Blog-Where a spiritual descendant of Sir William Osler and Abbie Hoffman holds forth on issues of medicine, media and politics. Mostly.
Then Trump’s tweet came on March 21. I won’t say much about this chapter of the saga other than to note that it should be self-evident that there is a high inverse correlation between any pronouncement Donald Trump makes and its truth value. Thus, the fact that he touted the drug (along with a second drug we don’t have time to go into, azithromycin) could be reasonably regarded a priori as clinically useless, or at least wildly overblown, simply by dint of the fact that Trump endorsed it.
Meanwhile, in Fantasyland, tales from a “simple, country doctor” were filling the airwaves of the magical hydroxychloroquine elixir. The doctor in question is one Vladimir Zelenko, who noted that he was “seeing tremendous results” in patients using hydroxychloroquine, azithromycin, and zinc. How could such a simple country doctor outwit such heavyweights as Anthony Fauci, who seemed to remain stubbornly skeptical of hydroxychloroquine when doctors like Zelenko could see its obvious promise? Was Fauci secretly part of the Deep State trying to take down Trump by making things worse and withholding lifesaving, and readily available, drugs?
The answer to these questions are simple: Zelenko’s simple. He is, like his President who took to the Twitterverse in enthusiastic endorsement, a living, breathing, perfect example of the Dunning-Kruger effect. He is so hopelessly in over his head that he has no mental tools to understand just how in over his head he really is. Maybe–maybe–if COVID were as lethal as Ebola, simple country doctors could see for themselves if a drug worked without having to resort to clinical trials, or troublesome issues like placebo controls and informed consent, or confidence intervals and power calculations. But with this virus? Not so much. You need the machinery of modern medicine, and the research tools that took two centuries to develop, to really know whether you’re making an impact. But he has no clue that he has no clue. And so can be said for the followers of Donald Trump, who have been remarkably resistant to grasp his obvious buffoonery, despite it being on daily display over the past month. It’s quite impressive, really. Denial is a powerful thing.
But let’s end not on the cartoonish stupidity of the President and his Republican enablers, let’s turn back to what under normal circumstances would a be solid place to find information, for even they can make the occasional slip-up. And this week, a piece in the New York Times described a new trial on hydroxychloroquine in which the results were favorable. It’s certainly a better study than the one mentioned above, though that’s a pretty low hurdle. But it’s not substantially better: it once again enrolled too small a cohort to look directly at mortality, so it relies on surrogate data that make it hard to know whether the benefit is real or an optical illusion; the patient population studied never got very sick, making its relevance in saving lives of unclear significance; and people did suspiciously well in this cohort, potentially suggesting some unseen bias that shaped the numbers. Everyone in my division took a look at the paper: the reaction was swift, and it wasn’t anywhere near as favorable as the warm coverage in the article.
The study hasn’t been peer reviewed, where these and other troubling issues would be addressed. Perhaps upon peer review, the study might not even be published because it is found to be wanting. The question, then, is why did NYT pick it up? At the Billy Rubin Blog, we’re scratching our heads on that one, because the publication of this article just made it harder for every ID doctor everywhere to try to do their jobs, in no small part because we have to continuously explain to stressed and worried families at length why these studies aren’t really very good, and that these drugs come with side effects that might actually end their loved ones life, not save it. This blog entry, despite running to thousands of words, hasn’t even taken a shot at explaining a heart-stopping effect called the long QT syndrome, which is almost certainly hydroxychloroquine’s most deadly acute effect, and is even worse when used in conjunction with azithromycin, and which I’ve seen once already in a COVID patient.
Ultimately, there’s an old saying in medicine that encapsulates the skepticism that we should be applying toward hydroxychloroquine’s boosters, whether those boosters are motivated by naked partisan political considerations (which is to say, Trump, who wants this to go away for narrowly selfish reasons), or by a look-we’re-trying-to-do-everything-we-can motivation (doctors who feel they just can’t stand around and do nothing). The saying is really old, so old that it comes from a different language, and a different epoch, entirely. The language is Latin, and the saying is primum non nocere. It means, “first, do no harm,” and is a caution to physicians who panic in the midst of an outbreak by trying to throw everything at the wall and seeing what sticks. With a four percent case fatal virus, you cannot see what sticks unless you do a clinical trial. With a drug like hydroxychloroquine, off-the-shelf use is a recipe for killing not only one patient–the COVID patient receiving the drug–but possibly a second as well. That person is the lupus patient who has been denied their drug. Because soon, stockpiles of hydroxychloroquine, like the ventilators that are crucial to the survival of the sickest COVID patients, will have dried up.
Dr. Zelenkos Response:
On July 2nd, over 60 da, Dr Zelenko does another interview with Dr. Drew Pinsky on his podcast -Dose of Dr. Drew. In this session he elaborates on his treatment and progress.
Dr Pinsky, mentions that he himself has been using hydroxochlroquine for patients with rheumatoid issues most of his career with no side effects what so ever.
Dr Zelenko stresses the importance of zinc in the process, but zinc has trouble getting into the cell. A Substance like hydroxychloroquine assists in getting the Zinc into that Cell. He uses the analogy of a gun and a bullet. In this scenario Hydroxychloroquine is the gun amd zinc is the bullet. One can’t work without the other. He also mentions that, because of the negative press, there are times that hydroxychloroquine is not an option. When that happens, he substitutes Quercetin, which can be purchased over the counter.
In this interview, both doctors delve into the “Prolonged QTC ” issue and it basically being a non issue. In the outpatient setting.
At this point Dr. Zelenko’s trials have shown his approach gas an 84% reduction in hospitalization and 99% survival rate against the control group. Trials were being peer reviewed t this point. To get the full breath of the interview, I recommend you click on the link below. This interview was not taken down by you-tube
American Frontline Doctors Summit
A group of doctors appeared on the Front of the Nations Capitol steps for a press conference, within hours the video went viral amassing over 17 million within 8 hours, with over 185,000 concurrent viewers
Then the games began, within hours Facebook, Twitter and You-Tube had squashed the press conference under their perception that it was massive misinformation and they had to protect citizens. The media attack dogs were next drawing blood anywhere and anyplace they could.
CNN: A video featuring a group of doctors making false and dubious claims related to the coronavirus was removed by Facebook, Twitter, and YouTube after going viral online Monday. The video, published by the right-wing media outlet Breitbart News, featured a group of people wearing white lab coats calling themselves “America’s Frontline Doctors” staging a press conference in front of the US Supreme Court in Washington, DC.
Washington Post-After social media companies removed a viral video showing doctors spreading unsubstantiated information about the novel coronavirus, a phrase inspired by one doctor’s past claims began trending on Twitter: demon sperm. It turns out Stella Immanuel has a history of making particularly outlandish statements — including that the uterine disorder endometriosis is caused by sex with demons that takes place in dreams.
A video published by Breitbart shows a group of doctors saying unproven, false and misleading claims about the coronavirus pandemic. Social media platforms said they were removing the video because the claims contained in it were untrue.
Contrary to what the video claims, there is no known cure for COVID-19. Hydroxychloroquine is not a proven treatment, and public health officials advise everyone to wear face masks in public.
The video also makes misleading claims about state hydroxychloroquine restrictions, coronavirus case numbers and the impact of nationwide shutdown orders.
It appears that the detractors use 5 minutes from the 44 min video on Dr. Stella Emmanuel, where she categorizes her treatment as a cure(True that aspect has not been proven to any degree) a reason to take down and censor all the remaining doctors and their statements.( Are we in Russia, Danny, I don’t think were in Russia) They also used a couple of past sermons from the Dr. that were off the beaten past to say the least. However, I cannot find a source that proves her success rate from her treatments are suspect. I ask that you view these videos in their entirety, before you make your judgement.
(pls note that Dr. Simone Gold, MD, JD, FABEM, pictured in the front above, was terminated from her position for participating in the summit)
Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford Health System Study Shows
Pls note excerpts from this study published on 7/02/2020
DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System.
In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s six hospitals, the study found 13% of those treated with hydroxychloroquine alone died compared to 26.4% not treated with hydroxychloroquine. None of the patients had documented serious heart abnormalities; however, patients were monitored for a heart condition routinely pointed to as a reason to avoid the drug as a treatment for COVID-19.
The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).
Patients treated with hydroxychloroquine at Henry Ford met specific protocol criteria as outlined by the hospital system’s Division of Infectious Diseases. The vast majority received the drug soon after admission; 82% within 24 hours and 91% within 48 hours of admission. All patients in the study were 18 or over with a median age of 64 years; 51% were men and 56% African American.
“The findings have been highly analyzed and peer-reviewed,” said Dr. Marcus Zervos, division head of Infectious Disease for Henry Ford Health System, who co-authored the study with Henry Ford epidemiologist Samia Arshad. “We attribute our findings that differ from other studies to early treatment, and part of a combination of interventions that were done in supportive care of patients, including careful cardiac monitoring. Our dosing also differed from other studies not showing a benefit of the drug. And other studies are either not peer reviewed, have limited numbers of patients, different patient populations or other differences from our patients.”
Zervos said the potential for a surge in the fall or sooner, and infections continuing worldwide, show an urgency to identifying inexpensive and effective therapies and preventions.
“We’re glad to add to the scientific knowledge base on the role and how best to use therapies as we work around the world to provide insight,” he said. “Considered in the context of current studies on the use of hydroxychloroquine for COVID-19, our results suggest that the drug may have an important role to play in reducing COVID-19 mortality.”
The Key to Defeating COVID-19 Already Exists. We Need to Start Using It | Opinion
As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.
I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.
On May 27, I published an article in the American Journal of Epidemiology (AJE) entitled, “Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis.” That article, published in the world’s leading epidemiology journal, analyzed five studies, demonstrating clear-cut and significant benefits to treated patients, plus other very large studies that showed the medication safety.
Physicians who have been using these medications in the face of widespread skepticism have been truly heroic. They have done what the science shows is best for their patients, often at great personal risk. I myself know of two doctors who have saved the lives of hundreds of patients with these medications, but are now fighting state medical boards to save their licenses and reputations. The cases against them are completely without scientific merit.
Since publication of my May 27 article, seven more studies have demonstrated similar benefit. In a lengthy follow-up letter, also published by AJE, I discuss these seven studies and renew my call for the immediate early use of hydroxychloroquine in high-risk patients. These seven studies include: an additional 400 high-risk patients treated by Dr. Vladimir Zelenko, with zero deaths; four studies totaling almost 500 high-risk patients treated in nursing homes and clinics across the U.S., with no deaths; a controlled trial of more than 700 high-risk patients in Brazil, with significantly reduced risk of hospitalization and two deaths among 334 patients treated with hydroxychloroquine; and another study of 398 matched patients in France, also with significantly reduced hospitalization risk. Since my letter was published, even more doctors have reported to me their completely successful use.
Beyond these studies of individual patients, we have seen what happens in large populations when these drugs are used. These have been “natural experiments.” In the northern Brazil state of Pará, COVID-19 deaths were increasing exponentially. On April 6, the public hospital network purchased 75,000 doses of azithromycin and 90,000 doses of hydroxychloroquine. Over the next few weeks, authorities began distributing these medications to infected individuals. Even though new cases continued to occur, on May 22 the death rate started to plummet and is now about one-eighth what it was at the peak.
A reverse natural experiment happened in Switzerland. On May 27, the Swiss national government banned outpatient use of hydroxychloroquine for COVID-19. Around June 10, COVID-19 deaths increased four-fold and remained elevated. On June 11, the Swiss government revoked the ban, and on June 23 the death rate reverted to what it had been beforehand. People who die from COVID-19 live about three to five weeks from the start of symptoms, which makes the evidence of a causal relation in these experiments strong. Both episodes suggest that a combination of hydroxychloroquine and its companion medications reduces mortality and should be immediately adopted as the new standard of care in high-risk patients.
Why has hydroxychloroquine been disregarded?
First, as all know, the medication has become highly politicized. For many, it is viewed as a marker of political identity, on both sides of the political spectrum. Nobody needs me to remind them that this is not how medicine should proceed. We must judge this medication strictly on the science. When doctors graduate from medical school, they formally promise to make the health and life of the patient their first consideration, without biases of race, religion, nationality, social standing—or political affiliation. Lives must come first.
Second, the drug has not been used properly in many studies. Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. Even so, it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.
In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.
Third, concerns have been raised by the FDA and others about risks of cardiac arrhythmia, especially when hydroxychloroquine is given in combination with azithromycin. The FDA based its comments on data in its FDA Adverse Event Reporting System. This reporting system captured up to a thousand cases of arrhythmias attributed to hydroxychloroquine use. In fact, the number is likely higher than that, since the reporting system, which requires physicians or patients to initiate contact with the FDA, appreciably undercounts drug side effects.
But what the FDA did not announce is that these adverse events were generated from tens of millions of patient uses of hydroxychloroquine for long periods of time, often for the chronic treatment of lupus or rheumatoid arthritis. Even if the true rates of arrhythmia are ten-fold higher than those reported, the harms would be minuscule compared to the mortality occurring right now in inadequately treated high-risk COVID-19 patients. This fact is proven by an Oxford University study of more than 320,000 older patients taking both hydroxychloroquine and azithromycin, who had arrhythmia excess death rates of less than 9/100,000 users, as I discuss in my May 27 paper cited above. A new paper in the American Journal of Medicine by established cardiologists around the world fully agrees with this.
In the future, I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence. But for now, reality demands a clear, scientific eye on the evidence and where it points. For the sake of high-risk patients, for the sake of our parents and grandparents, for the sake of the unemployed, for our economy and for our polity, especially those dis-proportionally affected, we must start treating immediately.
Use this blog as your contact point and advise your congressperson and senator that they are on notice. Go to the Senate and congressman information at the top of this blog, if you are on a tablet or smartphone click on “Menu”. That will take you to each states congress and senate contact information, including phone numbers, addresses and social media. Contact today and let them know you expect them to extol the virtues of hydroxychloroquine, political issues and self agendas be damned.
Thank you for participating in this conversation. God Bless America and Godspeed.